Combinations ; - see below
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Betanase | Zydus Cadila Healthcare | C.Mehta & Co Ltd. | 5mg | 150 | Tablet | per tablet | KES 370 |
| Betanase | Zydus Cadila Healthcare | C.Mehta & Co Ltd. | 5mg | 1000 | Tablet | per tablet | KES 958 |
| Daonil | Sanofi Aventis | Surgipharm Ltd | 5mg | 30 | Tablet | per tablet | KES 380.00 |
| Daonil | Sanofi Aventis | Surgipharm Ltd | 5mg | 100 | Tablet | per tablet | KES 1,264.00 |
| Euglucon | Roche | Roche Products | 5mg | 100 | Tablet | per tablet | KES 1,524 |
| Glemide- | West Coast Pharmaceuticals Works Ltd | Ray Pharmaceuticals Ltd | 5mg | 100 | Tablet | per tablet | KES 150 |
| Glibenclamide | Laboratory & Allied Ltd. | Laboratory & Allied Ltd | 5mg | 1000 | Tablet | per tablet | KES 750.00 |
| Glibenclamide | Laboratory & Allied Ltd. | Laboratory & Allied Ltd | 5mg | 500 | Tablet | per tablet | KES 900 |
| Glibenclamide | Laboratory & Allied Ltd. | Laboratory & Allied Ltd | 5mg | 100 | Tablet | per tablet | KES 300 |
| Glibetic- | Flamingo Heat Pad | Harley's Limited | 5mg | 100 | Tablet | per tablet | KES 70 |
| Gliboral | Menarini Pharmaceuticals | Phillips Pharmaceuticals Ltd. | 5mg | 60 | Tablet | per tablet | KES 438.00 |
| Glicon | Efroze Chemical Industries Ltd | Njimia Pharmaceuticals Ltd. | 5mg | 60 | Tablet | per tablet | KES 260 |
| Glimide | Laboratory & Allied Ltd. | Laboratory & Allied Ltd | 5mg | 100 | Tablet | per tablet | KES 80.00 |
| Glitisol | Remedica Ltd. | Twokay Chemicals Ltd | 5mg | 100 | Tablet | per tablet | KES 270.00 |
| Melix | Lagap SA Pharmaceuticals | Pharma Specialities Ltd. | 5mg | 100 | Tablet | per tablet | KES 600 |
| Nogluc | Cosmos Limited. | Cosmos Limited | 5mg | 28 | Tablet | per tablet | KES 75 |
| Nogluc | Cosmos Limited. | Cosmos Limited | 5mg | 120 | Tablet | per tablet | KES 270 |
| Betanese | Zydus Cadila Healthcare | Harley's Limited | 5mg | 150 | Tablet | per tablet | KES 190.00 |
| Betanese | Zydus Cadila Healthcare | Harley's Limited | 5mg | 1000 | Tablet | per tablet | KES 958.00 |
| Glemide-5 | West Coast Pharmaceuticals Works Ltd | Ray Pharmaceuticals Ltd | 5mg | 100 | Tablet | per tablet | KES 150.00 |
| Glibenclamide | Arrow Generics | Metro Pharmaceuticals Ltd (Uganda) | 5mg | 100 | Tablet | per tablet | KES 300.00 |
| Glibetic-5 | Flamingo Pharmaceuticals Ltd. | Harley's Limited | 5mg | 100 | Tablet | per tablet | KES 82.00 |
| Glibetic-5 | Flamingo Pharmaceuticals Ltd. | Harley's Limited | 5mg | 1000 | Tablet | per tablet | KES 500.00 |
| Glibil | Hikma Pharmaceuticals | Goodman Agencies Ltd | 5mg | 30 | Tablet | per tablet | KES 370.00 |
| Retanese | Zydus Cadila Healthcare | Harley's Limited | 5mg | 150 | Tablet | per tablet | KES 177.00 |
| Glibenclamide more info | |
|---|---|
| Mode Of Action | Sulphonylurea -antidiabetics like chlorpropamide act mainly by directly stimulating the release of insulin from functioning beta cells of pancreatic islet tissue. To achieve this, they inhibit the ATP-potassium channels on the beta cell membrane and potassium efflux. This results in depolarization and calcium influx, calcium-calmodulin binding, kinase activation, and release of insulin-containing granules by exocytosis. |
| Drug Indication | Uncomplicated and non-ketonic diabetes mellitus (maturity onset type II diabetes) |
| Precautions | Maintain regular medical monitoring; elderly; barbiturate therapy; dietetic therapy in obese; Addisons disease; and disulfiram-like reactions. |
| Contra-Indications | Diabetes complicated by keto-acidosis; coma; Raynauds disease; pregnancy; gangrene; severe trauma; fever; severe renal/hepatic/thyroid function impairment; juvenile diabetes mellitus; severe and unstable diabetes; severe inflammation. |
| Side Effects | GI disturbances; blood dyscrasia; hypoglycaemia; jaundice; skin rashes; hypersensitivity reactions; headache; dizziness; oedema; hyponatraemia; paraesthesia; photosensitivity. |
| Dosage | Initially 2.5mg daily before first meal. Increased by 2.5mg until blood sugar is under control (max 15mg daily, max. Single dose 10mg) |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS AFFECTING NUTRITION AND METABOLISM |
| Drug Sub-Category | Insulins |